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The MEK/ERK Pathway is the Primary Conduit for Borrelia burgdorferi-Induced Inflammation and P53-Mediated Apoptosis in Oligodendrocytes

Lyme neuroborreliosis (LNB) affects both the central and peripheral nervous systems. In a rhesus macaque model of LNB we had previously shown that brains of rhesus macaques inoculated with Borrelia burgdorferi release inflammatory mediators, and undergo oligodendrocyte and neuronal cell death. In vi...

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Hlavní autoři: Parthasarathy, Geetha, Philipp, Mario T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947362/
https://ncbi.nlm.nih.gov/pubmed/24114360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-013-0913-8
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