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Inflammatory mediator release from primary rhesus microglia in response to Borrelia burgdorferi results from the activation of several receptors and pathways

BACKGROUND: In previous studies, neurons were documented to undergo apoptosis in the presence of microglia and live Borrelia burgdorferi, but not with either agent alone. Microscopy showed that several Toll-like receptors (TLRs) were upregulated in microglia upon B. burgdorferi exposure. It was hypo...

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Publicat a:J Neuroinflammation
Autors principals: Parthasarathy, Geetha, Philipp, Mario T
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396743/
https://ncbi.nlm.nih.gov/pubmed/25889406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0274-z
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