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Long Term Human Reconstitution and Immune Aging in NOD-Rag (−)-γ chain (−) Mice
Aging of the human immune system is characterized by a gradual loss of immune function and a skewing of hematopoiesis toward the myeloid lineage, a reduction in the lymphocytic lineage, and progressive increases in senescent memory T cells at the expense of naïve T cells. Both the innate and the ada...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947178/ https://ncbi.nlm.nih.gov/pubmed/24094417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2013.08.013 |
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