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Sequence-dependent combination therapy with doxorubicin and a survivin-specific small interfering RNA nanodrug demonstrates efficacy in models of adenocarcinoma

The clinical management of cancer reflects a balance between treatment efficacy and toxicity. While typically, combination therapy improves response rate and time to progression compared with sequential monotherapy, it causes increased toxicity. Consequently, in cases of advanced cancer, emerging gu...

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Detalles Bibliográficos
Main Authors: Ghosh, Subrata K., Yigit, Mehmet V., Uchida, Masashi, Ross, Alana W., Barteneva, Natalie, Moore, Anna, Medarova, Zdravka
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947151/
https://ncbi.nlm.nih.gov/pubmed/24114765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28499
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