A Theranostic Small Interfering RNA Nanoprobe Protects Pancreatic Islet Grafts From Adoptively Transferred Immune Rejection

Islet transplantation has recently emerged as an acceptable clinical modality for restoring normoglycemia in patients with type 1 diabetes mellitus (T1DM). The long-term survival and function of islet grafts is compromised by immune rejection–related factors. Downregulation of factors that mediate i...

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Главные авторы: Wang, Ping, Yigit, Mehmet V., Ran, Chongzhao, Ross, Alana, Wei, Lingling, Dai, Guangping, Medarova, Zdravka, Moore, Anna
Формат: Artigo
Язык:Inglês
Опубликовано: American Diabetes Association 2012
Предметы:
Immunology and Transplantation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501867/
https://ncbi.nlm.nih.gov/pubmed/22923469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0441
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