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A Theranostic Small Interfering RNA Nanoprobe Protects Pancreatic Islet Grafts From Adoptively Transferred Immune Rejection

Islet transplantation has recently emerged as an acceptable clinical modality for restoring normoglycemia in patients with type 1 diabetes mellitus (T1DM). The long-term survival and function of islet grafts is compromised by immune rejection–related factors. Downregulation of factors that mediate i...

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Main Authors: Wang, Ping, Yigit, Mehmet V., Ran, Chongzhao, Ross, Alana, Wei, Lingling, Dai, Guangping, Medarova, Zdravka, Moore, Anna
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501867/
https://ncbi.nlm.nih.gov/pubmed/22923469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0441
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