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Class III β-tubulin overexpression within the tumor microenvironment is a prognostic biomarker for poor overall survival in ovarian cancer patients treated with neoadjuvant carboplatin/paclitaxel

Critics have suggested that neoadjuvant chemotherapy (NACT) followed by interval debulking may select for resistant clones or cancer stem cells when compared to primary cytoreduction. β-tubulins are chemotherapeutic targets of taxanes and epothilones. Class III β-tubulin overexpression has been link...

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Autors principals: Roque, Dana M., Buza, Natalia, Glasgow, Michelle, Bellone, Stefania, Bortolomai, Ileana, Gasparrini, Sara, Cocco, Emiliano, Ratner, Elena, Silasi, Dan-Arin, Azodi, Masoud, Rutherford, Thomas J., Schwartz, Peter E., Santin, Alessandro D.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947146/
https://ncbi.nlm.nih.gov/pubmed/24005572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-013-9614-5
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