Tubulin-β-III Overexpression by Uterine Serous Carcinomas is a Marker for Poor Overall Survival after Platinum/Taxane Chemotherapy and Sensitivity to Epothilones

BACKGROUND: Uterine serous carcinoma (USC) is a subtype of endometrial cancer associated with chemoresistance and poor outcome. Overexpression of tubulin-β-III and p-glycoprotein has been linked to paclitaxel resistance in many cancers but has been undercharacterized among USC. Epothilones have demo...

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Detalhes bibliográficos
Main Authors: Roque, Dana M., Bellone, Stefania, English, Diana P., Buza, Natalia, Cocco, Emiliano, Gasparrini, Sara, Bortolomai, Ileana, Ratner, Elena, Silasi, Dan-Arin, Azodi, Masoud, Rutherford, Thomas J., Schwartz, Peter E., Santin, Alessandro D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700638/
https://ncbi.nlm.nih.gov/pubmed/23585021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28017
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