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Binding to any ESCRT can mediate ubiquitin-independent cargo sorting
The ESCRT machinery is known to sort ubiquitinated transmembrane proteins into vesicles that bud into the lumen of multivesicular bodies (MVBs). Although the ESCRTs themselves are ubiquitinated they are excluded from the intraluminal vesicles and recycle back to the cytoplasm for further rounds of s...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947099/ https://ncbi.nlm.nih.gov/pubmed/24148098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12135 |
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