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Binding to any ESCRT can mediate ubiquitin-independent cargo sorting

The ESCRT machinery is known to sort ubiquitinated transmembrane proteins into vesicles that bud into the lumen of multivesicular bodies (MVBs). Although the ESCRTs themselves are ubiquitinated they are excluded from the intraluminal vesicles and recycle back to the cytoplasm for further rounds of s...

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Autors principals: Mageswaran, Shrawan Kumar, Dixon, Megan Gorringe, Curtiss, Matt, Keener, James P., Babst, Markus
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947099/
https://ncbi.nlm.nih.gov/pubmed/24148098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12135
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