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Constitutively active ESCRT-II suppresses the MVB-sorting phenotype of ESCRT-0 and ESCRT-I mutants

The endosomal sorting complex required for transport (ESCRT) protein complexes function at the endosome in the formation of intraluminal vesicles (ILVs) containing cargo proteins destined for the vacuolar/lysosomal lumen. The early ESCRTs (ESCRT-0 and -I) are likely involved in cargo sorting, wherea...

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Bibliografske podrobnosti
izdano v:Mol Biol Cell
Main Authors: Mageswaran, Shrawan Kumar, Johnson, Natalie K., Odorizzi, Greg, Babst, Markus
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310745/
https://ncbi.nlm.nih.gov/pubmed/25501366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-10-1469
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