Regulation of cargo transfer between ESCRT-0 and ESCRT-I complexes by flotillin-1 during endosomal sorting of ubiquitinated cargo

Ubiquitin-dependent sorting of membrane proteins in endosomes directs them to lysosomal degradation. In the case of receptors such as the epidermal growth factor receptor (EGFR), lysosomal degradation is important for the regulation of downstream signalling. Ubiquitinated proteins are recognised in...

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Bibliografiske detaljer
Udgivet i:Oncogenesis
Main Authors: Meister, M, Bänfer, S, Gärtner, U, Koskimies, J, Amaddii, M, Jacob, R, Tikkanen, R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519196/
https://ncbi.nlm.nih.gov/pubmed/28581508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.47
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