Regulation of cargo transfer between ESCRT-0 and ESCRT-I complexes by flotillin-1 during endosomal sorting of ubiquitinated cargo

Ubiquitin-dependent sorting of membrane proteins in endosomes directs them to lysosomal degradation. In the case of receptors such as the epidermal growth factor receptor (EGFR), lysosomal degradation is important for the regulation of downstream signalling. Ubiquitinated proteins are recognised in...

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Publicado en:Oncogenesis
Autores principales: Meister, M, Bänfer, S, Gärtner, U, Koskimies, J, Amaddii, M, Jacob, R, Tikkanen, R
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519196/
https://ncbi.nlm.nih.gov/pubmed/28581508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.47
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