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Role of Stoichiometry in the Dimer-Stabilizing Effect of AMPA Receptor Allosteric Modulators

[Image: see text] Protein dimerization provides a mechanism for the modulation of cellular signaling events. In α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors, the rapidly desensitizing, activated state has been correlated with a weakly dimeric, glutamate-binding domain confo...

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Main Authors: Ptak, Christopher P., Hsieh, Ching-Lin, Weiland, Gregory A., Oswald, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2013
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947009/
https://ncbi.nlm.nih.gov/pubmed/24152170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb4007166
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