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Modulation of AMPA Receptor Gating by the Anticonvulsant Drug, Perampanel

[Image: see text] Postsynaptic AMPA/glutamate receptors, essential for neuronal excitability, are important targets for anticonvulsant therapy. This single channel study of the selective noncompetitive AMPA receptor antagonist, perampanel, was performed on homotetrameric GluA3 receptor-channels that...

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Bibliografische gegevens
Gepubliceerd in:ACS Med Chem Lett
Hoofdauteurs: Yuan, Christine L., Shi, Edward Y., Srinivasan, Jayasri, Ptak, Christopher P., Oswald, Robert E., Nowak, Linda M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2018
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421588/
https://ncbi.nlm.nih.gov/pubmed/30891119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00322
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