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Compartmental models for apical efflux by P-glycoprotein. Part 1. Evaluation of model complexity
PURPOSE: With the goal of quantifying P-gp transport kinetics, Part 1 of these manuscripts evaluates different compartmental models and Part 2 applies these models to kinetic data. METHODS: Models were developed to simulate the effect of apical efflux transporters on intracellular concentrations of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3946900/ https://ncbi.nlm.nih.gov/pubmed/24019023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1164-7 |
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