Llwytho...

Type I interferon-dependent activation of NK cells by rAd28 or rAd35, but not rAd5, leads to loss of vector-insert expression

Vaccines constructed from rare-serotype recombinant adenovirus vectors (rAd) such as rAd serotype 28 (rAd28) and rAd35 are currently being explored as alternatives to rAd5-based vaccines because they circumvent the problems with pre-existing immunity that complicate the effectiveness of rAd5 vaccine...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Johnson, Matthew J., Björkström, Niklas K., Petrovas, Constantinos, Liang, Frank, Gall, Jason G.D., Loré, Karin, Koup, Richard A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946768/
https://ncbi.nlm.nih.gov/pubmed/24325826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.11.055
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