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Adenovirus type-35 vectors block human CD4(+) T-cell activation via CD46 ligation
Recombinant adenoviruses (rAds) based on types 5 (rAd5) and 35 (rAd35) have emerged as important vaccine delivery vectors in clinical testing for a variety of pathogens. A major difference between these vectors is their binding to cellular receptors used for infection. Whereas rAd5 binds coxsackie-a...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3088631/ https://ncbi.nlm.nih.gov/pubmed/21502499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017146108 |
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