Adenovirus type-35 vectors block human CD4(+) T-cell activation via CD46 ligation

Recombinant adenoviruses (rAds) based on types 5 (rAd5) and 35 (rAd35) have emerged as important vaccine delivery vectors in clinical testing for a variety of pathogens. A major difference between these vectors is their binding to cellular receptors used for infection. Whereas rAd5 binds coxsackie-a...

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Hlavní autoři: Adams, William C., Gujer, Cornelia, McInerney, Gerald, Gall, Jason G. D., Petrovas, Constantinos, Hedestam, Gunilla B. Karlsson, Koup, Richard A., Loré, Karin
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088631/
https://ncbi.nlm.nih.gov/pubmed/21502499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017146108
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