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Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor.

APO-1 (Fas/CD95), a member of the tumor necrosis factor receptor superfamily, induces apoptosis upon receptor oligomerization. In a search to identify intracellular signaling molecules coupling to oligomerized APO-1, several cytotoxicity-dependent APO-1-associated proteins (CAP) were immunoprecipita...

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Published in:EMBO J
Main Authors: Kischkel, F C, Hellbardt, S, Behrmann, I, Germer, M, Pawlita, M, Krammer, P H, Peter, M E
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394672/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8521815/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00245.x
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