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TGF-β Signaling in Hepatocytes Participates in Steatohepatitis Through Regulation of Cell Death and Lipid Metabolism
Transforming growth factor (TGF)-β signaling activates Smad-dependent and TAK1-dependent signaling to regulate cell survival, proliferation, fibrosis, and tumorigenesis. The effects of TGF-β signaling on metabolic syndrome including non-alcoholic fatty liver disease remain elusive. Wild-type (WT) an...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3946696/ https://ncbi.nlm.nih.gov/pubmed/23996730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26698 |
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