TGF-β Signaling in Hepatocytes Participates in Steatohepatitis Through Regulation of Cell Death and Lipid Metabolism

Transforming growth factor (TGF)-β signaling activates Smad-dependent and TAK1-dependent signaling to regulate cell survival, proliferation, fibrosis, and tumorigenesis. The effects of TGF-β signaling on metabolic syndrome including non-alcoholic fatty liver disease remain elusive. Wild-type (WT) an...

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Bibliographic Details
Main Authors: Yang, Ling, Roh, Yoon Seok, Song, Jingyi, Zhang, Bi, Liu, Cheng, Loomba, Rohit, Seki, Ekihiro
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946696/
https://ncbi.nlm.nih.gov/pubmed/23996730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26698
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