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TLR2 and TLR9 contribute to alcohol-mediated liver injury through induction of CXCL1 and neutrophil infiltration

Although previous studies reported the involvement of the TLR4-TRIF pathway in alcohol-induced liver injury, the role of TLR2 and TLR9 signaling in alcohol-mediated neutrophil infiltration and liver injury has not been elucidated. Since alcohol binge drinking is recognized to induce more severe form...

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Publicado en:Am J Physiol Gastrointest Liver Physiol
Autores principales: Roh, Yoon Seok, Zhang, Bi, Loomba, Rohit, Seki, Ekihiro
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491507/
https://ncbi.nlm.nih.gov/pubmed/25930080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00031.2015
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