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Pilot Trial: Pregabalin on Colonic Sensorimotor Functions in Irritable Bowel Syndrome

BACKGROUND: In prior studies, pregabalin reduced rectal or colonic pain in patients with irritable bowel syndrome (IBS) and healthy adults, suggesting reduction of afferent function. AIM: To assess effects of pregabalin on colonic compliance, sensory and motor functions in patients with constipation...

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Autors principals: Iturrino, Johanna, Camilleri, Michael, Busciglio, Irene, Burton, Duane, Zinsmeister, Alan R.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946640/
https://ncbi.nlm.nih.gov/pubmed/24095618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dld.2013.09.002
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