Losartan reverses permissive epigenetic changes in renal glomeruli of diabetic db/db mice

Epigenetic mechanisms such as chromatin histone H3 lysine methylation and acetylation have been implicated in diabetic vascular complications. However, histone modification profiles at pathologic genes associated with diabetic nephropathy in vivo and their regulation by the angiotensin II type 1 rec...

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Bibliografski detalji
Glavni autori: Reddy, Marpadga A., Sumanth, Putta, Lanting, Linda, Yuan, Hang, Wang, Mei, Mar, Daniel, Alpers, Charles E., Bomsztyk, Karol, Natarajan, Rama
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946617/
https://ncbi.nlm.nih.gov/pubmed/24088954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.387
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