Preferential binding of human topoisomerase I to superhelical DNA.

Eukaryotic type I DNA topoisomerase provides swivels for removing torsional strain from the DNA helix during transcription and DNA replication. Previously it has been shown that the enzyme is associated with actively transcribed genes and replicating DNA. Using an inactive mutant form of the protein...

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Bibliografski detalji

Izdano u:	EMBO J
Glavni autori:	Madden, K R, Stewart, L, Champoux, J J
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 1995
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394649/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7489729/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00224.x
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