Preferential binding of human topoisomerase I to superhelical DNA.

Eukaryotic type I DNA topoisomerase provides swivels for removing torsional strain from the DNA helix during transcription and DNA replication. Previously it has been shown that the enzyme is associated with actively transcribed genes and replicating DNA. Using an inactive mutant form of the protein...

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書目詳細資料

發表在:	EMBO J
Principais autores:	Madden, K R, Stewart, L, Champoux, J J
格式:	Artigo
語言:	Inglês
出版:	Nature Publishing Group 1995
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394649/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7489729/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00224.x
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