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Modulation of T(reg) function improves adenovirus vector-mediated gene expression in the airway
Virus vector -mediated gene transfer has been developed as a treatment for cystic fibrosis (CF) airway disease, a lethal inherited disorder caused by somatic mutations in the CFTR gene. The pathological pro-inflammatory environment of CF as well as the naïve and adaptive immunity induced by the viru...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3946346/ https://ncbi.nlm.nih.gov/pubmed/24385144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.78 |
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