Homotropic Cooperativity from the Activation Pathway of the Allosteric Ligand-Responsive Regulatory Protein TRAP()

The trp RNA-binding Attenuation Protein (TRAP) assembles into an 11-fold symmetric ring that regulates transcription and translation of trp-mRNA in bacilli via heterotropic allosteric activation by the amino acid tryptophan (Trp). Whereas nuclear magnetic resonance studies have revealed that Trp-ind...

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Hlavní autoři: Kleckner, Ian R., McElroy, Craig A., Kuzmic, Petr, Gollnick, Paul, Foster, Mark P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946311/
https://ncbi.nlm.nih.gov/pubmed/24224873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401364v
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