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Mechanistic Models Fit to Variable Temperature Calorimetric Data Provide Insights into Cooperativity
Allostery pervades macromolecular function and drives cooperative binding of ligands to macromolecules. To decipher the mechanisms of cooperative ligand binding it is necessary to define at a microscopic level the structural and thermodynamic consequences of binding of each ligand to its allosterica...
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| Publicado no: | Biophys J |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5390055/ https://ncbi.nlm.nih.gov/pubmed/28402876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.02.031 |
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