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Mechanisms of Allosteric Gene Regulation by NMR Quantification of μs-ms Protein Dynamics
The trp RNA-binding attenuation protein (TRAP) is a paradigmatic allosteric protein that regulates the tryptophan biosynthetic genes associated with the trp operon in Bacilli. The ring-shaped 11-mer TRAP is activated for recognition of a specific trp-mRNA target by binding up to 11 tryptophan molecu...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258336/ https://ncbi.nlm.nih.gov/pubmed/22115774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.11.019 |
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