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β-Agonists Selectively Modulate Proinflammatory Gene Expression in Skeletal Muscle Cells via Non-Canonical Nuclear Crosstalk Mechanisms

The proinflammatory cytokine Tumour Necrosis Factor (TNF)-α is implicated in a variety of skeletal muscle pathologies. Here, we have investigated how in vitro cotreatment of skeletal muscle C2C12 cells with β-agonists modulates the TNF-α-induced inflammatory program. We observed that C2C12 myotubes...

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Detalhes bibliográficos
Main Authors: Kolmus, Krzysztof, Van Troys, Marleen, Van Wesemael, Karlien, Ampe, Christophe, Haegeman, Guy, Tavernier, Jan, Gerlo, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946252/
https://ncbi.nlm.nih.gov/pubmed/24603712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090649
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