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The XTT Cell Proliferation Assay Applied to Cell Layers Embedded in Three-Dimensional Matrix

Cell proliferation, a main target in cancer therapy, is influenced by the surrounding three-dimensional (3D) extracellular matrix (ECM). In vitro drug screening is, thus, optimally performed under conditions in which cells are grown (embedded or trapped) in dense 3D matrices, as these most closely m...

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Bibliografiske detaljer
Main Authors: Huyck, Lynn, Ampe, Christophe, Van Troys, Marleen
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419859/
https://ncbi.nlm.nih.gov/pubmed/22574651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2011.391
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