Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin.

Rhodniin is a highly specific inhibitor of thrombin isolated from the assassin bug Rhodnius prolixus. The 2.6 Angstrum crystal structure of the non-covalent complex between recombinant rhodniin and bovine alpha-thrombin reveals that the two Kazal-type domains of rhodniin bind to different sites of t...

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Publié dans:	EMBO J
Auteurs principaux:	van de Locht, A, Lamba, D, Bauer, M, Huber, R, Friedrich, T, Kröger, B, Höffken, W, Bode, W
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394622/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7489704/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00199.x
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