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Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin.

Rhodniin is a highly specific inhibitor of thrombin isolated from the assassin bug Rhodnius prolixus. The 2.6 Angstrum crystal structure of the non-covalent complex between recombinant rhodniin and bovine alpha-thrombin reveals that the two Kazal-type domains of rhodniin bind to different sites of t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: van de Locht, A, Lamba, D, Bauer, M, Huber, R, Friedrich, T, Kröger, B, Höffken, W, Bode, W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC394622/
https://ncbi.nlm.nih.gov/pubmed/7489704
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