Protective Effect of Metformin Against Cisplatin-Induced Ototoxicity in an Auditory Cell Line

Metformin, an antidiabetic drug with potent anticancer activity, is known to prevent oxidative stress-induced cell death in several cell types through a mechanism dependent on the mitochondria. In the present study, we investigated the influence of metformin on cisplatin ototoxicity in an auditory c...

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Bibliografiske detaljer
Main Authors: Chang, Jiwon, Jung, Hak Hyun, Yang, Ji Yoon, Lee, Sehee, Choi, June, Im, Gi Jung, Chae, Sung Won
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946136/
https://ncbi.nlm.nih.gov/pubmed/24297263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-013-0431-y
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