Protective Role of Trimetazidine Against Neomycin-induced Hair Cell Damage in Zebrafish

OBJECTIVES: Trimetazidine (TMZ) is known to reduce the generation of oxygen-derived free radicals. The objective of the present study was to evaluate the effects of TMZ on neomycin-induced ototoxicity in transgenic zebrafish (Brn3C: EGFP). METHODS: Five-day, postfertilization zebrafish larvae were e...

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Main Authors: Chang, Jiwon, Im, Gi Jung, Chae, Sung Won, Lee, Seung Hoon, Kwon, Soon-Young, Jung, Hak Hyun, Chung, Ah-Young, Park, Hae-Chul, Choi, June
Format: Artigo
Language:Inglês
Published: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2013
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863670/
https://ncbi.nlm.nih.gov/pubmed/24353861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3342/ceo.2013.6.4.219
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