Protective Effect of Metformin on Gentamicin-Induced Vestibulotoxicity in Rat Primary Cell Culture

OBJECTIVES: One of the antidiabetic drugs, metformin, have shown that it prevented oxidative stress-induced death in several cell types through a mechanism involving the opening of the permeability transition pore and cytochrome c release. Thus, it is possible that the antioxidative effect of metfor...

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Vydáno v:Clin Exp Otorhinolaryngol
Hlavní autoři: Lee, Ji Young, Lee, Se Hee, Chang, Ji Won, Song, Jae-June, Jung, Hak Hyun, Im, Gi Jung
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240486/
https://ncbi.nlm.nih.gov/pubmed/25436048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3342/ceo.2014.7.4.286
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