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Acquired resistance to dasatinib in lung cancer cell lines conferred by DDR2 gatekeeper mutation and NF1 loss

The treatment of non-small cell lung cancer has evolved dramatically over the past decade with the adoption of widespread use of effective targeted therapies in patients with distinct molecular alterations. In lung squamous cell carcinoma (lung SqCC) recent studies have suggested that DDR2 mutations...

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Autors principals: Beauchamp, Ellen M., Woods, Brittany A., Dulak, Austin M., Tan, Li, Xu, Chunxiao, Gray, Nathanael S., Bass, Adam J., Wong, Kwok-kin, Meyerson, Matthew, Hammerman, Peter S.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946067/
https://ncbi.nlm.nih.gov/pubmed/24296828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0817
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