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Considerations for clinical read alignment and mutational profiling using next-generation sequencing
Next-generation sequencing technologies are increasingly being applied in clinical settings, however the data are characterized by a range of platform-specific artifacts making downstream analysis problematic and error- prone. One major application of NGS is in the profiling of clinically relevant m...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
F1000Research
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3945748/ https://ncbi.nlm.nih.gov/pubmed/24627757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.1-2.v2 |
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