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Naive CD4 T-cell activation identifies MS patients having rapid transition to progressive MS

OBJECTIVE: Our objective was to determine whether altered naive CD4 T-cell biology contributes to development of disease progression in secondary progressive multiple sclerosis (SPMS). METHODS: We compared the naive CD4 T-cell gene expression profiles of 19 patients with SPMS and 14 healthy controls...

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Detalhes bibliográficos
Main Authors: Zastepa, Evelyn, Fitz-Gerald, Leslie, Hallett, Michael, Antel, Jack, Bar-Or, Amit, Baranzini, Sergio, Lapierre, Yves, Haegert, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945666/
https://ncbi.nlm.nih.gov/pubmed/24453076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000146
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