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Predicting cancer drug mechanisms of action using molecular network signatures()

Molecular signatures are a powerful approach to characterize novel small molecules and derivatized small molecule libraries. While new experimental techniques are being developed in diverse model systems, informatics approaches lag behind these exciting advances. We propose an analysis pipeline for...

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Bibliographic Details
Main Authors: Pritchard, Justin R., Bruno, Peter M., Hemann, Michael T., Lauffenburger, Douglas A.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945388/
https://ncbi.nlm.nih.gov/pubmed/23287973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2mb25459j
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