Glucose-dependent de Novo Lipogenesis in B Lymphocytes: A REQUIREMENT FOR ATP-CITRATE LYASE IN LIPOPOLYSACCHARIDE-INDUCED DIFFERENTIATION

Bacterially derived lipopolysaccharide (LPS) stimulates naive B lymphocytes to differentiate into immunoglobulin (Ig)-secreting plasma cells. Differentiation of B lymphocytes is characterized by a proliferative phase followed by expansion of the intracellular membrane secretory network to support Ig...

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Detalhes bibliográficos
Main Authors: Dufort, Fay J., Gumina, Maria R., Ta, Nathan L., Tao, Yongzhen, Heyse, Shannon A., Scott, David A., Richardson, Adam D., Seyfried, Thomas N., Chiles, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945362/
https://ncbi.nlm.nih.gov/pubmed/24469453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.551051
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