Molecular Determinants Mediating Gating of Transient Receptor Potential Canonical (TRPC) Channels by Stromal Interaction Molecule 1 (STIM1)

Transient receptor potential canonical (TRPC) channels mediate a critical part of the receptor-evoked Ca(2+) influx. TRPCs are gated open by the endoplasmic reticulum Ca(2+) sensor STIM1. Here we asked which stromal interaction molecule 1 (STIM1) and TRPC domains mediate the interaction between them...

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Detalhes bibliográficos
Main Authors: Lee, Kyu Pil, Choi, Seok, Hong, Jeong Hee, Ahuja, Malini, Graham, Sarabeth, Ma, Rong, So, Insuk, Shin, Dong Min, Muallem, Shmuel, Yuan, Joseph P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945304/
https://ncbi.nlm.nih.gov/pubmed/24464579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.546556
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