Resolution of central nervous system astrocytic and endothelial sources of CCL2 gene expression during evolving neuroinflammation

BACKGROUND: The chemokine CCL2 is a critical mediator of neuroinflammation in diseases such as multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). CCL2 drives mononuclear cell infiltration into the central nervous system (CNS), alters expression and distrib...

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Bibliographic Details
Main Authors: Shrestha, Bandana, Ge, Shujun, Pachter, Joel S
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Short Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944978/
https://ncbi.nlm.nih.gov/pubmed/24589378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-11-6
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