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Using Systems Approaches to Address Challenges for Clinical Implementation of Pharmacogenomics

Many genetic variants have been shown to affect drug response through changes in drug efficacy and likelihood of adverse effects. Much of pharmacogenomic science has focused on discovering and clinically implementing single gene variants with large effect sizes. Given the increasing complexities of...

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書誌詳細
主要な著者: Karnes, Jason H, Van Driest, Sara, Bowton, Erica A, Weeke, Peter E, Mosley, Jonathan D, Peterson, Josh F, Denny, Joshua C, Roden, Dan M
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944797/
https://ncbi.nlm.nih.gov/pubmed/24319008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wsbm.1255
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