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Using Systems Approaches to Address Challenges for Clinical Implementation of Pharmacogenomics
Many genetic variants have been shown to affect drug response through changes in drug efficacy and likelihood of adverse effects. Much of pharmacogenomic science has focused on discovering and clinically implementing single gene variants with large effect sizes. Given the increasing complexities of...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3944797/ https://ncbi.nlm.nih.gov/pubmed/24319008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wsbm.1255 |
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