Mesothelin Overexpression Is a Marker of Tumor Aggressiveness and Is Associated with Reduced Recurrence-free and Overall Survival in Early-Stage Lung Adenocarcinoma

PURPOSE: In an effort to identify molecular markers of tumor aggressiveness and therapeutic targets in lung adenocarcinoma (ADC), we investigated the expression of mesothelin (MSLN) in lung ADC, as well as its biological and clinical relevance. EXPERIMENTAL DESIGN: In a training and validation set o...

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Detalhes bibliográficos
Main Authors: Kachala, Stefan S., Bograd, Adam J., Villena-Vargas, Jonathan, Suzuki, Kei, Servais, Elliot L., Kadota, Kyuichi, Chou, Joanne, Sima, Camelia S., Vertes, Eva, Rusch, Valerie W., Travis, William D., Sadelain, Michel, Adusumilli, Prasad S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944669/
https://ncbi.nlm.nih.gov/pubmed/24334761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1862
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