Mesothelin overexpression promotes mesothelioma cell invasion and MMP-9 secretion in an orthotopic mouse model and in epithelioid pleural mesothelioma patients

PURPOSE: Mesothelin (MSLN) is a tumor-associated antigen, being investigated as a biomarker and therapeutic target in malignant pleural mesothelioma (MPM). The biological function of MSLN overexpression in MPM is unknown. We hypothesized that MSLN may promote tumor invasion in MPM, a tumor character...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Servais, Elliot L., Colovos, Christos, Rodriguez, Luis, Bograd, Adam J., Nitadori, Jun-ichi, Sima, Camelia, Rusch, Valerie W., Sadelain, Michel, Adusumilli, Prasad S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759995/
https://ncbi.nlm.nih.gov/pubmed/22371455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2614
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados