Activation of TAK1 by MYD88 L265P drives malignant B-cell Growth in non-Hodgkin lymphoma

Massively parallel sequencing analyses have revealed a common mutation within the MYD88 gene (MYD88(L265P)) occurring at high frequencies in many non-Hodgkin lymphomas (NHLs) including the rare lymphoplasmacytic lymphoma, Waldenström's macroglobulinemia (WM). Using whole-exome sequencing, Sange...

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Detalhes bibliográficos
Main Authors: Ansell, S M, Hodge, L S, Secreto, F J, Manske, M, Braggio, E, Price-Troska, T, Ziesmer, S, Li, Y, Johnson, S H, Hart, S N, Kocher, J-P A, Vasmatzis, G, Chanan-Kahn, A, Gertz, M, Fonseca, R, Dogan, A, Cerhan, J R, Novak, A J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944662/
https://ncbi.nlm.nih.gov/pubmed/24531446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2014.4
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