Loading...

Consequences of the recurrent MYD88(L265P) somatic mutation for B cell tolerance

MYD88(L265P) has recently been discovered as an extraordinarily frequent somatic mutation in benign monoclonal IgM gammopathy, Waldenström’s macroglobulinemia, and diffuse large B cell lymphoma. In this study, we analyze the consequences for antigen-activated primary B cells of acquiring MYD88(L265P...

Full description

Saved in:
Bibliographic Details
Main Authors: Wang, James Q., Jeelall, Yogesh S., Beutler, Bruce, Horikawa, Keisuke, Goodnow, Christopher C.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949567/
https://ncbi.nlm.nih.gov/pubmed/24534189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131424
Tags: Add Tag
No Tags, Be the first to tag this record!