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BAFF-R Specific Activation of TRAF6 and the PI3K-Pathway in Lymphoma B Cells

BAFF-R is the primary BAFF receptor that is responsible for promoting B-cell development and survival. Malignant B-cells exploit the BAFF/BAFF receptor system and high serum BAFF levels or genetic alterations in BAFF receptors have been found in B-cell cancers. BAFF signaling impacts pro-survival pa...

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Библиографические подробности
Главные авторы: Secreto, Frank, Manske, Michelle, Price-Troska, Tammy, Ziesmer, Steven, Hodge, Lucy S., Ansell, Stephen M., Cerhan, James R., Novak, Anne J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110115/
https://ncbi.nlm.nih.gov/pubmed/24206092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2013.862619
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