Multiple components of the spliceosome regulate Mcl1 activity in neuroblastoma

Cancer treatments induce cell stress to trigger apoptosis in tumor cells. Many cancers repress these apoptotic signals through alterations in the Bcl2 proteins that regulate this process. Therapeutics that target these specific survival biases are in development, and drugs that inhibit Bcl2 activiti...

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Autors principals: Laetsch, T W, Liu, X, Vu, A, Sliozberg, M, Vido, M, Elci, O U, Goldsmith, K C, Hogarty, M D
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944256/
https://ncbi.nlm.nih.gov/pubmed/24556687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.40
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