Knockdown of BAG3 induces epithelial–mesenchymal transition in thyroid cancer cells through ZEB1 activation

The process by which epithelial features are lost in favor of a mesenchymal phenotype is referred to as epithelial–mesenchymal transition (EMT). Most carcinomas use this mechanism to evade into neighboring tissues. Reduction or a loss of E-cadherin expression is a well-established hallmark of EMT. A...

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Hlavní autoři: Meng, X, Kong, D-H, Li, N, Zong, Z-H, Liu, B-Q, Du, Z-X, Guan, Y, Cao, L, Wang, H-Q
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944249/
https://ncbi.nlm.nih.gov/pubmed/24577090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.32
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